Electron Microscopy Core Facility

Member of Biocenter Finland and Biocenter Kuopio

The Microscopy Laboratory located on the Kuopio campus has its foundations in the Department of Electron Microscopy, established in the 1970s. The laboratory plays a regionally significant role, particularly in the fields of electron microscopy and imaging spectroscopy, as well as with regard to demanding sample-preparation techniques, particularly for biological samples.

Full list of our equipment can be found on Equipment Infrastructure page

Main Equipment

A modern, high-resolution transmission electron microscope (TEM), was acquired in 2010. Operated either at acceleration voltage of 80 kV or 200 kV, the system is capable of studying biological samples and samples related to materials science at the level of individual atoms. Clinical diagnostics conducted at Kuopio University Hospital, among others, relies on our equipment.

In 2012–2014, the laboratory acquired a high-resolution scanning electron microscope (SEM), which allows the study of samples' surface structures at high resolution, as well as the determination of the elemental composition of samples. The procurement was undertaken together with Savonia University of Applied Sciences and Kuopio University Hospital, with the Regional Council of Pohjois-Savo (ERDF) as the principal source of funding.

Sample preparation facilities

In the sample-preparation laboratory for electron microscopy, samples are processed in accordance with the protocols agreed with customers (researchers or companies). Ultra-thin (approximately 50 nanometres) cross-sections for inspection by TEM or, for example, dried and gold-coated samples for SEM inspection, are prepared. During years 2014-15 special equipment for processing of challenging specimens from the material science was be acquired. Based on ion borbardment, these equipment can be used to prepare, e.g. cross-sections of multi-layer coatings or pharmaceutical materials for SEM or TEM analysis

Finland's only hard tissue laboratory providing commercial services is capable of processing biological tissues containing metal implants, for example. Large bone samples can also be cut for inspection by an optical microscope, such as in studies and diagnostics conducted in cooperation with the Bone and Cartilage Research Unit directed by Professor Heikki Kröger.

For additional information, please contact: Arto Koistinen