Title of the plenary talk: Tuning physical interaction with cells and tissues through spatial patterning of multiscale materials
Affiliation: Regenerative Medicine Program, Houston Methodist Research Institute
Vice Chair for Research, Orthopedics and Sports Medicine, Houston Methodist Hospital
- Biomimetic materials to improve tissue regeneration and modulate the immune response.
- Artificial biomimetic extracellular matrices for musculoskeletal drug delivery and regenerative medicine.
- Bio-inspired and cell-based delivery platforms for the active targeting of inflammation.
- Nanostructured hydrogels for the localized sustained release of clinically approved drugs.
- Development of new surgical procedures and clinical approaches using nano-based therapeutics.
Highlights of recent work:
Chiappini, C., et al. (2015). "Biodegradable silicon nanoneedles delivering nucleic acids intracellularly induce localized in vivo neovascularization." Nat Mater 14(5): 532-539.
Minardi, S., et al. (2014). "Multiscale Patterning of a Biomimetic Scaffold Integrated with Composite Microspheres." Small 10(19): 3943-3953.
Molinaro, R., et al. (2016). "Biomimetic proteolipid vesicles for targeting inflamed tissues." Nature Materials 15: 1037.
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