Ennio Tasciotti

Title of the plenary talk: Tuning physical interaction with cells and tissues through spatial patterning of multiscale materials

Affiliation: Regenerative Medicine Program, Houston Methodist Research Institute 

Vice Chair for Research, Orthopedics and Sports Medicine, Houston Methodist Hospital   

Scientific interests

  • Biomimetic materials to improve tissue regeneration and modulate the immune response. 
  • Artificial biomimetic extracellular matrices for musculoskeletal drug delivery and regenerative medicine. 
  • Bio-inspired and cell-based delivery platforms for the active targeting of inflammation. 
  • Nanostructured hydrogels for the localized sustained release of clinically approved drugs. 
  • Development of new surgical procedures and clinical approaches using nano-based therapeutics.

Highlights of recent work:

Chiappini, C., et al. (2015). "Biodegradable silicon nanoneedles delivering nucleic acids intracellularly induce localized in vivo neovascularization." Nat Mater 14(5): 532-539. 

Minardi, S., et al. (2014). "Multiscale Patterning of a Biomimetic Scaffold Integrated with Composite Microspheres."  Small 10(19): 3943-3953.

Molinaro, R., et al. (2016). "Biomimetic proteolipid vesicles for targeting inflamed tissues." Nature Materials 15: 1037.

More information available:

https://www.houstonmethodist.org/faculty/ennio-tasciotti/ 

https://scholar.google.com/citations?hl=en&user=d09hQ7kAAAAJ&view_op=list_works&sortby=pubdate