Animal welfare and 3R
The welfare of laboratory animals must be checked daily.
- Furthermore, the welfare has to be ensured and enhanced, when animals are bred, maintained or used in an experiment.
- If problems emerge, technicians contact the researcher and check the animals more frequently.
- Further actions will be agreed case by case together with the researcher.
- It is also important to agree, for how long the situation will be monitored and what will be done if there is no improvement.
- Further information can be found from the Postoperative care -page
Evaluation of welfare
- The state of animal welfare can be evaluated e.g. with Body Conditioning Scoring (BC1-5). (ref. Ullman-Culleré ja Foltz 1999, Lab Anim Sci 49(3)319-323).
- Severity of welfare problems criterions can be based e.g. on weight gain and feed/water intake.
HUMANE ENDPOINTS FOR RODENTS:
- > 20 % weight loss
- remarkable dehydration
- abnormal appearance, posture or behaviouir, reluctance to move
- remarkable signs of pain regardless of medication
NB. If animal doesn't eat, drink, defecate or urinate, it is not a useful humane endpoint in rodents, since these criterions are difficult to monitor precisely, especially in group housing
- Further information can be found e.g. from the following pages:
- ELLA - National Animal Ethics Committee
- OECD humane endpoint - guidelines
- CCAC humane endpoint - guidelines
- ILAR Journal humane endpont -theme number