Molecular, cell and tissue imaging

Molecular, cell and tissue imaging focuses on understanding how molecules, cells and tissues function and respond to external cues in normal and pathological states. Bridging scales from the nano- to the millimetre range with a temporal resolution of several seconds poses huge challenges for microscopy methods but also requires powerful computational approaches for data acquisition, processing and image analysis. The research opportunities for the applicants will include developments of various multimodal microscopy applications for both life science research and medical imaging applications such as: multiparameter and computer aided high content fluorescence imaging, combination of STimulated Emission Depletion and Ground State Depletion with automated confocal High Content light Microscopy and Fluorescence Lifetime Imaging Microscopy, super resolution microscopy, Electron tomography, integrated positron emission tomography scan with computed tomography, high resolution tomographic imaging (micro-nano scale) and scattering (nanoscale), high resolution transmission electron microscopy, Fourier Transform Infrared Imaging spectroscopy, Polarized light microscopy, Raman spectroscopy and single-photon emission computed tomography .

Research groups involved in this research area are: Cell and tissue biomechanics (University of Eastern Finland (UEF), Kuopio, Finland), Biomechanics  (Lund University (LU), Lund, Sweden), Laboratory of Biophysics (University of Turku (UTU), Turku, Finland), Department of Neuroscience and Biomedical Engineering (Aalto University (AALTO), Helsinki, Finland), Tampere University (Tampere, Finland), Cell and tissue level imaging (of musculoskeletal tissue) (Oulu University (OULU), Oulu, Finland) and Soft tissue characterization using quantitative MRI and novel x-ray based methods (OULU).