Genetics of Gene Regulation in Disease

Research Goals

We focus on the identification and molecular characterization of human genetic variation that alters the gene regulatory capacity of transcription factors and contributes to diseases with identified genetic component like type 2 diabetes. We also collaborate widely with research groups who need bioinformatic expertise.

Scientific and Societal Impact of Research

The identification and mechanistic characterization of new, truly causal human genetic variants in complex diseases offer tools for improved disease prediction, subtyping and personalized medicine solutions.


Academy of Finland, Diabetes Research Foundation


Luke Norton (San Antonio, Texas, USA), Jorma Palvimo, Carsten Carlberg, Markku Laakso, Jussi Pihlajamäki, Sari Viitala, Anna-Liisa Levonen, Jaana Hartikainen, Arto Mannermaa, Veli-Matti Kosma, Rainer Rauramaa, Timo Lakka, Markku Tammi, Kirsi Rilla, Jussi Paananen (UEF).